
CREATE Medicines CREATE Medicines is pioneering multi-immune programming with its versatile in vivo CAR platform. Our proprietary mRNA-LNP CARs and targeted receptor/LNP technologies enable direct programming of T cells, NK cells, and myeloid cells within the body—demonstrating first-in-human evidence of uptake, expression, and tolerable repeat dosing. What sets CREATE apart: • Proprietary receptor and RNA engineering, including retrotransposon-mediated stability options • Multi-lineage programming across immune cell types (T, NK, myeloid) • First-in-human clinical data confirming mechanism of action • Demonstrated tolerability with repeat dosing Therapeutic Developer

CREATE Medicines

CREATE Medicines is pioneering multi-immune programming with its versatile in vivo CAR platform. Our proprietary mRNA-LNP CARs and targeted receptor/LNP technologies enable direct programming of T cells, NK cells, and myeloid cells within the body—demonstrating first-in-human evidence of uptake, expression, and tolerable repeat dosing. What sets CREATE apart: • Proprietary receptor and RNA engineering, including retrotransposon-mediated stability options • Multi-lineage programming across immune cell types (T, NK, myeloid) • First-in-human clinical data confirming mechanism of action • Demonstrated tolerability with repeat dosing

Therapeutic Developer